I use the pour on, on the skin, Ivermectin pour on or Cydectin pour on. I use it, a couple times, I think it was 21 days apart. My Nigerian kept having crusty ears and on the nose plus some flakey skin on the body, so treating her for a fungus also was needed. I think the mites caused a seconday fungal infection to take hold. Others give Ivermectin injectable, and inject it, getting good results, but I'd rather pour on some stuff instead.