I feel weird asking for support but I am having a rough time right now. I have Juvenile Rheumatoid Arthritis. It has been acting up for the past two months. I was on predinisone for about a month. It helped but talk about insomnia and being manic. I have days where I just don't want to crawl out of bed because I am so tired and everything hurts. My doctor put me on Methotrexate and I hate it! It's low dose oral chemo. It makes me feel really sick! I can't eat anything for about 3 days after I take it. I just feel so nauseous! He wont give me anything for the nausea. It's really annoying me. I know he is trying to find the right dose, but running for the nearest trash can and no eating is really not fun! :angry: The worst part is that this stuff seems to have helped with the pain. And I think he thinks I am developing a resistance to the drug i have been taking for 5 years with great results! :tears: It's called Remicade. Next time I go in to get it they are going to test my blood to see if they can find any antibodies against it. Oh and he found that my white count is pretty low. He was saying it could be because he upped my dose of Remicade, but I doubt it. My white count was always fine until he put me on Methotrexate. So I am just feeling pretty low and frustrated right now. :sigh: I know things could always be worse and thats what I keep telling myself. But I am just tired of hurting.