[/QUOTE]Thiamine is the only effective therapy, and treatment can result in improvement within a few hours if the disease is caught early enough. Thiamine is an inexpensive veterinary prescription. Producers should always keep thiamine on hand; the most commonly available strength is 100 mg/ml. Dosage is based on the goat's weight (4-1/2 cc per 100 pounds liveweight for 100 mg/ml thiamine) and must be given every six hours on a 24-hour cycle until all symptoms have disappeared completely to avoid relapse. Thiamine, like all B vitamins, is water soluable, so the goat eliminates daily what it doesn't utilize in the rumen. A sick goat's rumen doesn't produce B vitamins, hence the importance of adding them to the goat each day until it gets well. Initially thiamine should be given IM (into the muscle) but can be given SQ (subcutaneously) or even orally after several days of treatment. Some thiamine comes in 500 mg/ml strength, making the required dosage 1 cc per 100 pounds bodyweight. If thiamine is unavailable but the producer has injectable multiple B vitamins, check the label for how much thiamine (Vitamin B1) is present. Fortified Vitamin B Complex contains 100 mg/ml of thiamine, so the 4-1/2 cc per 100 pounds bodyweight dosage is appropriate. Injectable multiple B vitamins containing only 25mg/ml of thiamine require four times the 100mg/ml dosage (18-1/2 cc) per 100 pounds bodyweight, so the producer can quickly see the importance of obtaining the proper strength of injectable B vitamins. The key to overcoming Goat Polio is early diagnosis and treatment. Complete recovery is possible under such circumstances.