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Hi and welcome! If I am not badly mistaken I believe they can come in heat as early as 3 months and then if not successfully bred they will come back into heat every 21 days (someone can correct me if I am wrong). Sometimes when they come in heat you will notice a bloody kind of discharge usually visible on their tail.. but not all Does do this. I am sure someone else can pitch in with some opinions as well
and once again, Welcome!