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Ivermectin Resistance: Where to Go From Here?

4007 Views 46 Replies 11 Participants Last post by  happybleats
I just did a fecal after deworming my doe Prim with ivermectin on the 2nd of April. I got only a 33% reduction in eggs so clearly it didn't work properly. I'm not sure where to go from here. She had a count of 600 and she's looking pretty bad. Famacha is a three, but her body condition is quite frankly terrible and her coat condition is looking quite rough. I have got to get her looking better. I have decided to treat her herbally, but I still want to know what type of chemical wormer I should try next in the future. I want to be able to have a chemical dewormer on hand in the future, but I feel like I don't want to try something for Prim right now that might not work. So what dewormer should I get on hand next?

Now for Prim's health, I'm going to do acute dosage of LOH parasite formula and garlic of course. What about EOs? How often should I do them for acute dosing? (I have oregano, orange, lemongrass, and a digestive blend). Should I give her redcell with her famacha being 3? Anything else I should give her in addition?
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Which worm is showing those counts?
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Sorry, forgot to mention that 馃槼. Barber Pole.
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That's a good question. I talked to my vet about this last week. He said it really depends on where you are and your herd. He said he has two large goat farms he services. Each right across the road from the other. He said valbazen works on one farm, but not the other and cydectin works on the opposite farm, but not the other. So, I guess you have to experiment until you find one that is going to work for your herd. He did say he has had good luck with Prohibit, but you have a very small margin of error with that one. Currently, I'm still having good luck with cydectin oral sheep drench.
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Yuck, those are some nasty blood sucking worms to have to deal with. My notes have Valbazen and Cydectin sheep drench as treatments for barber pole.
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When did you have the fecal done after you had wormed her?
If too soon, it can give a false number.
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I did the fecal today. Is ten days too soon?
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Hey, @happybleats and @NigerianDwarfOwner707, I thought I should tag you guys for my above herb questions, because I wasn't sure you'd see them because of my thread title. 馃槜
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Ten days after deworming should be ok.. on acute dosing of LOH ..I would follow the protocol offered on her web site.. when I do acute I dose double every hour for a day.. rest at night..then I do regular dose every 4 hours ..day 3-5 I do 4 times a day. Then daily until I see good famacha. This may be adjusted based in how bad the goat is.
To add essential oils..I do one drop each if what you have there and add 3 cc olive oil and drench each goat individually. When not in crisis I do herbs one day a week and oils another day of the week. If I see pale famacha or fecal shows load Increase we will do herbs 2 or 3 times a week and oils once or twice.
As for keeping a chemical on hand Cydectin sheep drench is good. Quest is good but super strong and I would not use in sickly or super heavy burdened goats.
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Keep in mind that if one Chem dewormer in a family stops being effective all in that family will follow shortly after. Cydectin and ivomectin are within the same family. Once both are exhausted..we will need another family all together.
Valbazen is a good one too.. for all but pregnant does;)
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Thanks so much, Cathy. So while I am reducing Prim's worm load, how often should I do the EOs?
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You can do them as often as you feel she needs..I would at least do 2 times a week.
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I have a doe that has a terrible time with Barberpole. I use Quest+. Its a horse dewormer. It shows great results in 2 days. I had tried Ivermectin.. without good results. So for Stormy, I bought her a year 1/2 ago. Her previous owner wormed on schedule. Hope this will help yours also.
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I have a doe that has a terrible time with Barberpole. I use Quest+. Its a horse dewormer. It shows great results in 2 days. I had tried Ivermectin.. without good results. So for Stormy, I bought her a year 1/2 ago. Her previous owner wormed on schedule. Hope this will help yours also.
I did a little looking into quest before I saw your post, what's the difference between Quest and Quest Plus?
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Quest is Moxidectin. Quest Plus is Moxidectin and praziquantel. So its a combination and is longer lasting active capabilities.
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I've been using a cocktail of a Ivermectin, Valbazon and Prohibit, followed the next day with a dose of oregano, lemongrass and bitter orange essential oils for anyone with a real heavy worm load. So far, so good. For now, anyway.
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I would try Ivermectin plus Valbazen together (separate syringe but dosed one after another) before using Prohibit or Quest.
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Probit is a strong dewormer..Quest is a strong dewormer. Using together is way powerful. I agree with Salty..I wouldnt risk it. Probit has been known to cause death when used in a down goat. We really need to be aware of all the risks when we start combining treatments. IMO I would choose one dewormer, do before and after fecals to check effectiveness. We need to know what is working and what is not. Some doing an OK job may need a second family of dewormer to push it over the edge. Not every dewormer or combo will work for everyone. We b
need to find what will work for our own situation. It's good we all share ideas..what worked and didn't work for us to help eachother start some where. It's scary that we are running out of choices. We really need to do our part in slowing resistance down. Sorry went on a binge there lol. 馃槆
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Sorry, forgot to mention that 馃槼. Barber Pole.

I recently ran into a problem with barber pole... I did cydectin every 10 days 3 times and my counts are down.. and valbazen with the first dose of cydectin.. i did my alpines, that were the source of the worms, with one dose of prohibit and there counts also went down..


PS.. i also did shots of vitamin b complex everyday until better.. It really help with the goats that stopped eating and were not doing good at all. I definitely think it saved some of my goats since the worms have been so bad lately.
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What have you done other than drench?
Have you moved them into a fresh 鈥渃lean鈥 paddock after you drench them?
Your vet should be able to test the worms for resistance and tell you what to use. Simply trying one after the other to see what works will create more dramas in the future as it builds resistance. If you鈥檙e just drenching them and leaving them in the same paddock it鈥檚 going to take a long time even if the drench is effective.
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