The Goat Spot Forum banner

Quest Plus Only Gave 42% Reduction

2813 Views 44 Replies 9 Participants Last post by  MellonFriend
I dewormed Bella with Quest Plus gel four days after she kidded. She had an EPG of 700 right before I gave it to her, and now 15 days later her EPG is 400. That's only a reduction of 42%. That's not really enough, am I right? What would you do at this point? Should I retreat with Quest plus? Should I try something else? Do nothing? What would you do? I did 1ml per 100lbs, by the way.
1 - 20 of 45 Posts
I personally would retreat. I like to do at least 2x 10 days apart to catch all the stages.
  • Like
Reactions: 2
Definitely don't give more quest plus. I remember reading on here (I think it was goathiker who said) that quest stays in their system for 28 days and you can overdose them if you give more too soon.
  • Like
Reactions: 4
Definitely don't give more quest plus. I remember reading on here (I think it was goathiker who said) that quest stays in their system for 28 days and you can overdose them if you give more too soon.
I found the threads:


  • Like
Reactions: 4
Technically it stays in the system longer as some members (@happybleats ?) have mentioned but I do see people booster at the 10 day mark with no problems. I'm not sure if I fully believe the 28 day argument as goats do metabolize meds so quickly and usually go downhill 10 days after a quest dose if not repeated.

The fecal should really be done at the 10 day mark, by 15 days you've already got new arrested larvae hatching.

I'd say since quest is simply cydectin, give a booster with cydectin sheep drench in combo with another class such as safeguard or valbazen. Then do that once more in 10 days.

Herbal regimen still ongoing for your herd?
  • Like
Reactions: 4
I'll be sure to do the fecal at ten days when I dose Prim.

I'd say since quest is simply cydectin, give a booster with cydectin sheep drench in combo with another class such as safeguard or valbazen. Then do that once more in 10 days
I'm not sure what you mean by this. Are you saying do cydectin as well as safeguard or valbazen as a next move? Or...

Herbal regimen still ongoing for your herd?
It is, but last year it didn't work for me during kidding season worm bloom. I dedicatedly tried to treat the high worm loads with herbs, garlic, and EOs, but it did not work. I'm not exactly sure why. Since then I switched from LOH to Fir Meadows, and it's been working for times of little stress, but for post kidding I didn't want to make the same mistake that I did last year of relying on the herbs alone. I've been doing the three days on four days off routine.
Quest is a much stronger formula then other cydectin formulas. (I have the numbers somewhere) It does stay in the system longer and suggested not boostering before 28 day mark. If booster is needed sooner, a different family of dewormer is best.
  • Like
Reactions: 2
I'm not sure what you mean by this. Are you saying do cydectin as well as safeguard or valbazen as a next move? Or...
At the very least you can give the same dewormer at a lower strength if you don't feel comfortable dosing quest again - that means cydectin sheep drench which is moxidectin which is the same as quest. But it should always be done with a second class of a benzimidazole or albendazole, safeguard or valbazen. Single worming at this point is a thing of the past for you.
  • Like
Reactions: 1
Quest is moxidectin (which is Cydectin)

Quest Plus is moxidectin + praziquantel

I would do another fecal after the 28 days are up as long as her FAMACHA is fine and she is acting fine.
  • Like
Reactions: 2
Quest is moxidectin (which is Cydectin)

Quest Plus is moxidectin + praziquantel

I would do another fecal after the 28 days are up as long as her FAMACHA is fine and she is acting fine.
I am aware the differences between quest and quest plus, but the plus with praziquantel is simply there to fight tapeworms and flatworms--it will not have an effect on gastrointestinal nematodes such as barberpole worm.
  • Like
Reactions: 5
At the very least you can give the same dewormer at a lower strength if you don't feel comfortable dosing quest again - that means cydectin sheep drench which is moxidectin which is the same as quest. But it should always be done with a second class of a benzimidazole or albendazole, safeguard or valbazen. Single worming at this point is a thing of the past for you.
I'd rather not spend the money on cydectin since I don't have great faith in chemicals at this point, could I get normal quest--not quest plus, since that is moxidectin and then dose that along with valbazen since I have that on hand?
I'd rather not spend the money on cydectin since I don't have great faith in chemicals at this point, could I get normal quest--not quest plus, since that is moxidectin and then dose that along with valbazen since I have that on hand?
Is her FAMACHA and body condition okay? Barring a fecal she looks good?
  • Like
Reactions: 1
could I get normal quest--not quest plus, since that is moxidectin and then dose that along with valbazen since I have that on hand?
I would still be cautious treating with Quest too soon. Even without the plus the strength of the Moxidectin is the same, your just removing the praziquantel.

I would try the herbals acutely now. See how it goes.
  • Like
Reactions: 2
Is her FAMACHA and body condition okay? Barring a fecal she looks good?
Her body condition is not very good. I need to check FAMACHA. She's nursing four right now so her condition going downhill could be due to that fact. In the past while lactating she has handled numbers in the 400 range just fine, but I will certainly check FAMACHA tomorrow.

I would try the herbals acutely now. See how it goes.
I think you are right. I didn't really want to do more chemicals anyway since I wanted to start milking her soon.

What is the Fir Meadows acute dosage you'd recommend @NigerianDwarfOwner707? I have both GI Soother and DWA. I also have EOs (sweet orange, oregano, lemongrass, Gut Aid Blend, and clove). Cathy, feel free to chime in too, I just figured Hannah would have more experience with Fir Meadows. ;)
  • Like
Reactions: 3
What worms are you attempting to kill? Quest + is for barber pole worms. Usually at the 10 day mark, either Safeguard or Ivermevtin. And thats after a fecal.
  • Like
Reactions: 2
What worms are you attempting to kill? Quest + is for barber pole worms. Usually at the 10 day mark, either Safeguard or Ivermevtin. And thats after a fecal.
Barberpole is what I'm dealing with. So you do Ivermectin or safeguard alone as a booster for quest?
  • Like
Reactions: 1
Yes, I use Land of havilah and not familiar with Fir meadow protocol. She may have that info on her web page?
  • Like
Reactions: 2
Do DWA and GI Soother at double the normal dose every 3 hours during the day for 3 days, then double the normal dose 2-3x per day for another 10 days.

Essential oils as per Cathy's usual program.

Add Tummy Trouble Paste 2x daily for 5 days:

1/2 teaspoon of cayenne, cinnamon, slippery elm bark powder, and ginger (can be substituted for a slice of raw ginger the size of a quarter about 1/2 cm thick). Blend with 1 raw clove of garlic, molasses, apple cider vinegar, and enough water to drench.
  • Like
Reactions: 2
Yes. I do blue pour on Ivermectin. 10 days after a fecal, following the Quest+. That way you get 3 dewormers to clean up. Since quest + is active up to 28days, the Ivermectin is slow introduced, and cleans up the egg laying strengthening the power if the Quest +.
Ive had 80 to 90% kill of BP.
  • Like
Reactions: 1
Do DWA and GI Soother at double the normal dose every 3 hours during the day for 3 days, then double the normal dose 2-3x per day for another 10 days.

Essential oils as per Cathy's usual program.

Add Tummy Trouble Paste 2x daily for 5 days:

1/2 teaspoon of cayenne, cinnamon, slippery elm bark powder, and ginger (can be substituted for a slice of raw ginger the size of a quarter about 1/2 cm thick). Blend with 1 raw clove of garlic, molasses, apple cider vinegar, and enough water to drench.
Do I need to space out the time between giving the DWA and GI Soother? Or can I give them at the same time?
1 - 20 of 45 Posts
This is an older thread, you may not receive a response, and could be reviving an old thread. Please consider creating a new thread.
Top