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Question about Toltrazuril

2605 Views 27 Replies 10 Participants Last post by  Wild Hearts Ranch
I used Corid last year during worm season and didn’t really get the results I wanted from it. So I have been looking for some Toltrazuril instead, which I think is stronger since you only dose twice (but I’m not sure how often). But I can’t seem to find it! Where do y’all get it from?
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Thank you so much! I just ordered some.
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Corid does not treat worms, in case you didn’t know. It kills cocci.
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Yes I have other dewormers for worms. Cocci always gets bad though, so I needed something stronger.
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We use Zuri-Cox which is toltrazuril as well.
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We use Zuri-Cox which is toltrazuril as well.
Have you gotten and used any recently? At the beginning of Covid toltrazuril was changed and now it separates and is very thick and hard to administer. Do you know how Zuri Cox compares? I’d sure think something that’s easy to use.
Also, where do you buy Zuri Cox?
Yes, jsut opened a bottle yesterday that I got a month ago. It was seperated. I put the lid on and turned it upside down and jit it against the milk stand a few good times. It mixed better. I get it from a place that's called Game Bird Supply. It looks a touch sketchy but I get it quickly and in perfect condition.

ETA: Here is the link ZURI-COX 5% 240ML
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Yes, jsut opened a bottle yesterday that I got a month ago. It was seperated. I put the lid on and turned it upside down and jit it against the milk stand a few good times. It mixed better. I get it from a place that's called Game Bird Supply. It looks a touch sketchy but I get it quickly and in perfect condition.

ETA: Here is the link ZURI-COX 5% 240ML
Thanks! Even if it’s not any easier to use, it sure is a lot cheaper. I’ll have to try some.
I don't know... I like the idea of toltrazuril a lot, it is so much more synergistic and safe for the body... but it seems to work best when used as a preventative as the mode is almost more like a vaccine.

"Our Toltrazuril 5% solution is suitable for both therapy and metaphylaxis, and acts as an effective tool for controlling coccidia-related problems. By damaging the intracellular developmental stages of Coccidia, toltraturazil affects schizonts, microgametes, and macrogametes without damaging the cell tissue of the host animal. Findings from studies suggest the drug interferes with the division of the nucleus and the activity of mitochondria, which is responsible for respiratory metabolism in the parasite. In the magrometes, toltrazuril damages wall-forming bodies, and in all intracellular developmental stages, severe vacuolisation occurs due to inflation of the endoplasmatic reticulum. Toltrazuril does not interfere with immune development, and usually does not require follow-up treatment, even in advanced infections (after three to five days). However, the efficacy of the drug is independent from the severity of the infection."

They say it right there, the efficacy depends on the severity. In really severe infections I haven't seen the best results. Though, it also doesn't seem to work forever as a one time dose early on either. So... it can be hit or miss.
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Just to add, this is why:

"If you can identify oocysts in fecal exam, the protozoa has completed its reproductive cycle. The drug can not penetrate the oocyst wall to kill this stage, but treatment at the first signs of a clinical case will still help to limit the severity and duration of the infection as the Toltrazuril will kill single cell stages that have not reproduced sexually yet."
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Hey! Another quick question about Toltrazuril. I just dosed my 4&5 week old kids with it as a preventative. How long do I wait until I do another dose? It says for treatment do again in ten days, but for continuing prevention how long do I wait? Thanks.
Every 21 days. ;)
Toltrazuril is great as prevention. I like using it along with the herbal and essential oils we use. Typically it's used once at 10 days to 3 weeks old then after stressors such as banding, severe weather or going to a new home.
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That’s great! Thank you! So far so good on Coccidia. I think I am going to do a fecal this week on several of the kids to see where everyone is at. They are 4-6 weeks old and gaining about 3 lbs a week.
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Hey! Does anyone know the milk and meat withdrawal times for Toltrazuril? I gave it to my dairy goat 8 days ago and I am weaning her kids today.
Hey! Does anyone know the milk and meat withdrawal times for Toltrazuril? I gave it to my dairy goat 8 days ago and I am weaning her kids today.
No no one does because it’s not FDA approved and has not been tested. There is a 90 day for horses in Australia
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No no one does because it’s not FDA approved and has not been tested. There is a 90 day for horses in Australia
Hmm. Ok. Well I guess I’ll wait until 10 days and see what happens.
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Hmm. Ok. Well I guess I’ll wait until 10 days and see what happens.
Good plan. That is one of the downfalls, sadly :/
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(y) ;)
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